Abstract

INVESTIGATION OF THE VIRAL PHYSIOLOGY: APPROACHES TO RECOGNITION INVOLVING ENZYMES, LECTINS AND GLYCOCONJUGATES AGAINST INFECTIONS

Lakhtin V.M.*, Lakhtin M.V., DavydkinV.Yu.

Abstract

In the overview, based mainly on own data, the current knowledge of protein/lectin-glycoconjugate general principles and relationships that can be applied to constituents of the "machine" target recognition units by viruses including examples of phages is accented. The multilevel and hierarchical nature of such system interactions is noted. The functional interrelationships of enzymebiotics, lectinbiotics, enzyme lectins, lectin enzymes and postbiotics are considered. Enzymes and lectins co-function as important network communicators and signals due to the multiple roles and functions in recognition of glycoconjugates, binding and coordinated action, influencing effectiveness of viral submachine blocks of recognition and further penetration into microbes. The prospects of using the contribution of affine recognition types with the participation of both bacterial and viral glycoconjugates in microecological control in terms of microbiocenoses, pro/post/synbiotic compartment and mucosal biotopes are accented. The data expand the possible ways of using the glycoconjugates and proteins recognizing them, as well as viruses (phages) and pro/post/symbiotic combinations in the fight against pathogens and infections for the prevention and therapy of diseases.

Keywords: Glycoconjugates; reception; assembling; machinery; lectinbiotics; enzymebiotics; enzyme lectins; lectinbiotics, lectin enzymes, synergy, communications; viruses; phages; probiotics; postbiotics; synbiotics; prophylaxis; therapy.