Abstract

THE ROLE OF GUAR GUM IN GUT AND OTHER DISORDERS

Dr. Priyanka Anjinappa*, Shilpa M., Samudha C. N., Kavya G.

Abstract

The powdered endosperm of the seeds of the leguminous crop Cyamopsis tetragonolobus is known as guar gum. Galactomannan, a polymer of d-galactose and d-mannose, is a complex polysaccharide found in the endosperm. When this hydroxyl group-rich polymer is introduced to water, hydrogen bonds are formed, giving the mixture a noticeable increase in viscosity and thickness. It is used in many different industries because of its thickening, emulsifying, binding, and gelling qualities; rapid solubility in cold water; broad pH stability; film-forming capacity; and biodegradability. It is widely used in the pharmaceutical, cosmetic, food, textile, paper, explosives, and toiletry industries, among other sectors. It is employed in pharmaceuticals as a controlled-release carrier, suspending, thickening, stabilizing, and as a tablet binder and disintegrant. Guar gum is a hydrocolloidal polysaccharide that is made up of the sugars mannose and galactose in a molecular ratio of 1:1.4–1:2. In medicine, it is used as a bulk-forming laxative, hypoglycemic, hypolipidemic, antibacterial, anti-proliferative, and appetite suppressant, and in Crohn's disease and colitis, among other conditions. The current analysis provides detailed information on the variety of medicinal, chemical, pharmacological, and industrial applications of guar gum. Modified guar gum is widely used in pharmaceutical applications due to its viscosity-enhancing properties.

Keywords: Guar gum, Gut health, gastrointestinal disorders, Anti-inflammatory, wound healing.