Abstract

FORMULATION AND EVALUATION OF ANTI-INFLAMMATORY HERBAL TOPICAL FORMULATION OF CISSUS QUADRANGULARIS L.

Biresh Kumar Sarkar*, Ravi Kumar, Prince Kumar, Palash Mandal, Vidya Bhusan
Pal, M. Devgan

Abstract

Herbal medicine now has been gained global acceptance due to their therapeutic values. Many researchers investigated herbal formulations recently to explore their medicinal value as well as quality compliances. Considering these facts present study involves formulation and evaluation of topical formulation of Cissus quadrangularis. Dispersion method was used for the preparation of formulation with varying ratio of ingredients. The various instrumental techniques were used for drug analysis like; Ultraviolet Spectroscopy, Fourier-transform Infrared Spectroscopy and HPTLC etc. The formulation was also evaluated for various quality parameters like; pH, viscosity, spreadability, in vitro drug release, etc. The formulations C2 was found to possess satisfactory results in terms of quality parameters like; viscosity, spreadability and in vitro drug release. FT-IR studies suggested no chemical interactions between the drugs and ingredient.

Keywords: Cissus quadrangularis, herbal medicine, topical formulation, quality control.