Abstract

IN VITRO ANTIOXIDANT EVALUATION OF GRACILARIA FERGUSONII USING VARIOUS SOLVENT EXTRACTS

Jenifer P. and C. P. Balakrishnan*

Abstract

The present study was made on in vitro evaluation of red algae G. fergusonii was determined by different solvent extract at different concentration (100, 250, 500, 750, 1000 μg ml-1) by NO and H2O2 radical scavenging activity was compare with standard ascorbic acid. IC50 values of NO radical scavenging activity of methanol, chloroform and aqueous extract were reported at 690.77, 222.77 and 1058.65 μg/ml respectively. IC50 values of H2O2 radical scavenging activity of methanol, chloroform and aqueous extract were reported at 983.76, 266.23 and 1525 μg/ml respectively. In the mean time the IC50 value of standard ascorbic acid was recorded for NO and H2O2 are 163.05μg/ml and 855.38μg/ml respectively. An IC50 values was found that chloroform extract is more effective in NO and H2O2 free radical scavenging than that of methanol and aqueous extracts.

Keywords: G. fergusonii, Free Radicals, Nitric Oxide (NO), Hydrogen Peroxide (H2O2).