Abstract

MULTICOMPONENT SYNTHESIS AND CHARACTERIZATION OF NEW 2-SUBSTITUTED DERIVATIVES OF 3-AMINO-4-IMINO-8- NITRO-2H-PYRAZOLO [3,4-e]PYRIMIDO[2,3- b][1,3]BENZOTHIAZOLE

Anil B. Chidrawar* and Rajkumar U. Pokalwar

Abstract

A simple and efficient method have been used for the synthesis of 2- substituted derivatives of 3-amino-4-imino-8-nitro-pyrazolo [3,4-e] pyrimido [2,3-b] [1,3] benzothiazole (III) obtained by the multicomponent reaction of 2-amino-6-nitro benzothiazole (I) and bis methylthio methylene malononitrile (II) on refluxed with hydrazine hydrate in the presence of 5 ml of dimethyl formamide with a pinch of anhydrous K2CO3. The structures for the synthesized compounds are assigned on the basis of IR, 1HNMR and Mass spectral studies.

Keywords: 2-amino-6-nitrobenzothiazole, bismethylthio methylene malononitrile, hydrazine hydrate, dimethyl formamide, potassium carbonate.