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WJPR

World Journal of Pharmaceutical Research

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An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

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Abstract

PREPERATION AND SPECTROANALYTICAL STUDIES OF TWO NEW AZODYES DERIVED FROM PROCAINE HYDROCHLORIDE AND METACLOPRAMIDE

Nuha Waleed Ali* and Asaad A. Ali

Abstract

This study involves the preparation of two new azodyes derived from [procaine hydrochloride and 4-aminoantipyrine] (L1), and [Metoclopramide hydrochloride and 4-amino, 5-hydroxynaphthalene- 2, 7-disulphonic acid disodium salt dihydrate] (L2). They have been described by FT- IR, NMR, Visible spectroscopic and TG techniques. The acid-base properties were studied at different pH values (2-12), then the ionization and protonation constants were determined. The solvents effect of different polarities was studied

Keywords: Metoclopramide, Azodyes, Ionization & Protonation constants and Spectral studies.

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