Abstract

FENITROTHION INDUCED CHANGES IN AMINO ACIDS PROFILE OF BIOMPHALARIA ALEXANDRINA MOLLUSCAN HOST OF SCHISTOSOMA MANSONI

*Naima Z. Mohamed and Hanan F. Aly

Abstract

Amino acid profiles of control and Fenitrothion treated normal control snails were investigated in a trail to correlate the amino acids profile of treated snails to their previously reported molluscicidal and biological effects. Amino acid profiles of the snails were greatly manipulated with the treatment of Fenitrothion sublethal concentration (LC25), The disturbed amino acid profiles of treated snails, reduction in total protein content and significant increase in protease enzyme activity while significant inhibition in steroid hormones (estriol and progesterone), were discussed in relation to the decrease in snail's egg laying capacity, reduction of their compatibility for the development of the schistosome larvae and cercarial penetration of mammalian skin and snails reproductive efficiency.

Keywords: Fenitrothion, Schistosoma mansoni, Biomphalaria alexandrina, amino acids.