Abstract

THE ASSOCIATION BETWEEN HIGH TITER ANTI-DS-DNA ANTIBODY AND ANTI- ENTAMOEBA HITOLYTICA ANTIBODY TITER

Dr. Ali Abdul Hussian Mahdi* and Suhab Khalid Ibrahim

Abstract

The study was designed to estimate the prevalence of ds-DNA antibody (ds-DNA) in 350 patients infected with Entamoeba histolytica. Diagnosis of ds-DNA & Entamoeba histolytica was done by using enzyme linked immune sorbent assay (ELISA) technique, their age ranged 15-40 years. The results were compared to control group which constitute of 50 apparently healthy men, their age ranged (15- 40) years which is compatible to study group age. It was observed that there is a positive correlation coefficient between ds-DNA & Entamoeba histolytica (r=0.35729). Also there is significantly difference (t-test, P< 0.05) between mean of ds-DNA and Entamoeba histolytica of patients and control groups. It was concluded that ds -DNA antibody associated with Entamoeba histolytica infection due to the damage in intestinal tissue.

Keywords: ds-DNA antibody, Entamoeba histolytica, ELISA.