Abstract

STUDY ON NEWLY SYNTHESIZED OF METAL HETEROCHELATES BASED ON NORFLOXACIN AND DICUMAROL DERIVATIVE: BIOLOGICAL ASSESSMENT

Ankit J. Shah, Ketan S. Patel and Dinesh S. Patel*

Abstract

Some newly heterochelates synthesized by reflux of different coumarin derivative, Norfloxacin and transition metal as Cu(II). The structures of the ligands and their copper complexes were investigated and confirmed by the elemental analysis, FT-IR, 1H-NMR, 13C-NMR, and mass spectral data. Thermal behavior of newly synthesized mixed ligand Cu(II) complexes were investigated by means of thermogravimetry, electronic spectra and magnetic measurements. The compounds were screened for their antimicrobial and antioxidant viewing using serial broth dilution method and Minimum Inhibitory Concentration (MIC) is determined.

Keywords: Norfloxacin, biological study, octahedral Complexes.