Abstract

SYNTHESIS OF 1,5-BENZODIAZEPINO AND S-TRIAZINO INCORPORATED DERIVATIVES OF PYRAZOLO (ISOXAZOLO) ANNULATED AZACARBAZOLES OF MEDICINAL INTEREST.

Vandana Singh*, Meenakshi Sharma and Vatsala Soni

Abstract

In consideration of the unprecedented biological potentials of the privileged nucleus of 1,5-benzodiazepines, s-triazines, pyrazoles, isoxazoles, azacarbazoles, an efficient protocol to the synthesis of (2,3- b)-pyrazolo (isoxazolo) fused azacarbazoles, incorporated on its 5- position with 1,5-benzodiazepine nucleus and on its 7-position with 4,6-biscyclopropylamino-2-triazinyl amine of medicinal interest has been described.

Keywords: 1,5-Benzodiazepine, s-triazine, privileged nucleus, carbazole, azacarbazole, pyrazole, isoxazole.