Abstract

PHARMACOGNOSTICAL PHYTOCHEMICAL AND LARVICIDAL ACTIVITY OF ETHANOLIC LEAF EXTRACT OF LUFFA ACUTANGULA (CUCURBITACEAE)

*R. Ramasubramania Raja, P. Vijayasanthi, G. Mydhili, M. Aswini, S. Seshadri, V.M. Rajesh and M. Sreenivasulu

Abstract

Luffa acutangula belongs to the family of cucurbitaceae. The macroscopical character of the luffa acutangula was colour, odour, size, shape; taste was performed for the evaluation of morphological identification character. The microscopical evaluation of luffa acutangula leaf was performed by using transverse section technique. The pharmacognostical like extractive value, loss on drying, crude fibre content was performed. Leaf powder the active constituents by using colour reaction test. Extraction was performed soxhelet apparatus by using the solvent ethanol. The ethanolic extract was analysed by using colour reactions based chemical tests. Thin layer chromatography used to identify the phytoconstituents. Drug powder with different chemical reagents used to perform the fluorescence tests by using visible light and UV at 366nm. The larvicidal activity was performed by using ethanolic extract of luffa acutangula.6 hours, 12 hours, 24 hours, 48 hours, 72 hours were noted the values. In different concentration of ethanolic extract of luffa acutangula like 10 mg/ml, 20 mg/ml, 40 mg/ml, 80 mg/ml and 160 mg/ml used to analyse the larvicidal activity. Dose depending manner the activity was responsed. Finally, we concluded the ethanolic extract of luffa acutangula have potential larvicidal activity in 80 mg/ml and 160 mg/ml.

Keywords: Luffa acutangula, alkaloids, saponins, carbohydrates, larvicidal.