Abstract

SCREENING OF ANTIOXIDANT AND ANTICANCER ACTIVITY IN CROTON BONPLANDIANUM LEAF AND STEM CRUDE EXTRACTS.

Dr. S. R. Divya and Dr. A. Chandra Mohan*

Abstract

The phytoconstituents were remarkably higher in the leaf than the stem of Croton bonplandianum. Antioxidant activity of Croton bonplandianum was elucidated by DPPH. The methanolic extracts of both the leaf and the stem has the elevated levels of scavenging property when compared to the other extracts. The cytotoxicity study was carried out for plant the leaf and stem extracts of Croton bonplandianum. These extracts were screened for its cytotoxicity against HepG2 cell lines at different concentrations to determine the % of Viability and % of toxicity by MTT assay. The results are graphically represented and the percentage of viability was found to decrease and the percentage of toxicity was found to be increasing with increasing concentration of the extracts.

Keywords: Anticancer, Antioxidant, Plant extract, DPPH and MTT assay.