Abstract

A CLINICAL COMPARATIVE STUDY OF SOME VISHAGHNA DRAVAYA AND ERAND TAIL IN THE MANAGEMENT OF AMAVATA

Dr. Bhupinder Singh* and Bhavna Singh

Abstract

Herbs are natural remedies for the disease with higher safety profile and efficacy. India has an ancient heritage of traditional herbal medicine in the form of Ayurved. Amavata (rheumatoid arthritis) is the most common disease that poses a considerable challenge to physicians. Therefore the present study was carried out to evaluate efficacy of some vishaghna dravayas (antitoxic drugs) (Nirgundi, Haridra, Marich, Sireesh) and Erand tail. For this study, 32 patients satisfying EULAR 2010[1] (European League against Rheumatism) criteria were enrolled from OPD of Himalayiya Ayurvedic Medical College, Dehradun. These patients were randomly divided in two groups, group A (trial drug) and group B (Erand tail). Both the groups have sixteen patients each. Duration of trial was four months. ACR[2] (American College of Rheumatology) response criteria were used to assess efficacy. The results of both groups showed highly significant improvement in parameters of clinical and physical disability. On the basis of CDAI[3] (Clinical Disease activity Index) scores the result was highly significant for group B (Erand tail) and significant for group A. Results of ESR (Erythrocyte sedimentation rate) and RA (Rheumatoid Arthritis factor) titer were also found significant in both groups and group B (Erand tail) showed better result than group A. The results of present study revealed that these drugs have potential to be used in the treatment of rheumatoid arthritis and Erand tail is more effective than trial drug.

Keywords: Ama, Amavata, clinical trial, Erand tail, Rheumatoid arthritis, Vishaghna.