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Abstract

REVIEW ON PELLETIZATION: TECHNIQUES, CHARACTERIZATION AND APPLICATIONS

Harshada Dattatraya Dalvi*, Dr. Nilesh Khutle, Priyanka Pawar and Abhijeet Kunwarpuriya

Abstract

Multi-particulate dosage forms are pharmaceutical formulations in which the active substance is present as a number of small independent subunits. Pellets are defined as spherical or semi- spherical, free flowing solid units with narrow size and diameter ranging from 0.5- 1.5mm. the present review outlines the merits and demerits of pellets, need of pelletization, formation and growth mechanism of pellets and pelletization techniques. It also briefs about the factors that affect pelletization techniques, their characterization and applications.

Keywords: Multiparticulates, pellets, techniques, characterization, applications.


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