Abstract

SYNTHESIS, CHARACTERISATION AND BIOLOGICAL EVALUATION OF A NEW SERIES OF BENZOFURANS

N. Vijaya Lakshmi*, V. Sandhya Reddy, S. K. Johny Basha, S. K. Shakeela Begum and D. Pavana Deepthi

Abstract

Present investigation deals with synthesis of a series benzofurans by using various chemicals like ethyl acetoacetate, salicylic acid, aminoguanidine, guanidine, chloro acetyl chloride, carbon disulphide, potassium hydroxide, resorcinol, acetylacetone, thionyl chloride, urea, hydrazine hydrate, hydrazine hydrochloride, thiourea, ethylacetate, methanol, potassium cardonate, thioglycollic acid. The synthesized complexes are characterised by using Melting point determination, Thin layer chromatography, Infrared spectroscopy, Nuclear magnetic resonance spectroscopy, Mass spectroscopy. The synthesised compounds were recrystallised with appropriate solvents. All the synthesised complexes are screened for their antibacterial activities.

Keywords: Benzofurans, Meltingpoint, TLC, IR, Massspectroscopy, NMR, Recrystallisation.