Abstract

IN-VITRO ANTIHELMINTHIC ACTIVITY, PHOTO CHEMICAL SCREENING AND TLC STUDIES OF METHANOL EXTRACTION ON CELOSIA CRISTATA FLOWER USING IN - STATE FESTIVAL OF TELANGANA (BATHUKAMMA)

P. Sravan Kumar*

Abstract

India being a rich and varied flora of medicinal plants. It’s used in traditional festivals of India. the present study deals with the in-vitro Antihelminthic activity phytochemical screening and TLC studies of methanol extraction on celosia cristata flower using in - state festival of Telangana (Bathukamma). methanol extraction on celosia cristata flower was used evaluation of phytochemical screening determination by some chemical tests and thin layer chromatographic study was carried out by using various solvent system of varying polarity of hexane, ethyl acetate, acetone. Phytochemical screening reflects presence of like carbohydrates, Alkolides, phenols, tannins, phytosterols, glycosides, flavonoids, tannies shows methanol solvents extracts. thin layer chromatographic studies of the celosia cristata flower parts constituted different colored phytochemical compounds with different Rf values. Methanol extractions of celosia cristata flower various concentrations (25, 50, 100mg/ml) of all extracts were tested and results were expressed in terms of time for paralysis and time for death of worms. piperazine citrate (10 mg/ml) was used as a reference standard and distilled water as a control group. treatment with concluded that the Methanol extract of celosia cristata flowers showed potent Anthelmintic activity and was equipotent to standard Anthelmintic drug. The potent Anthelmintic activity could be due to presence of glycosides, flavonoids and sterols. so, from the above findings, it was concluded that Methanol extract of celosia cristata flowers posse’s significant wormicide activity property.

Keywords: Celosia Cristata, Anthelmintic, Phytochemicals, TLC Profile.