Abstract

CHRONOTHERAPY: NEW APPROACH FOR TREATMENT

Dr. A. Bharathi*

Abstract

Chronotherapy is recent advanced appropriate technology drug delivery system. The drug is delivery to particular site with the specific time. It is also recognized as chronotropic drug delivery system. It any therapy based on the timing of physiologic and pathologic activities of human body. This process in which a person‟s daily activates are supposedly synchronized with a natural metabolic rhythm in a 24- hours cycle. The particular time those patients took a medication it as impact a treatment of suitable diseases. The disease symptoms circadian variations drug release to vary over time. Drug pharmacokinetics can also a time depended, variation of disease state and in plasma drug concentration. This drug delivery system designed to benefit of drug release with in short period of time, after predetermined a long time. This system is favorable drug delivery systems in circadian diseases like asthma, cardiovascular diseases, arthritis, and hypercholestremia Approaches are capsular system. Different types of barrier coated, stimuli sensitive pulsatile system and externally regulated system are synopsize in this article. These review articles focus on disease of chronotropic systems.

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