
![]() |
|||||||||||||
WJPR Citation
|
| All | Since 2020 | |
| Citation | 8502 | 4519 |
| h-index | 30 | 23 |
| i10-index | 227 | 96 |
STRATEGIES TO OVERCOME CHEMOTHERAPEUTIC DRUG RESISTANCE – A MINI REVIEW
R. Vimalavathini*, Sindhuja A., Sreemathy K. and Jagadesan R.
Abstract Chemotherapeutic drug resistance is a grave problem in cancer therapy. Novel ways of therapeutic targeting must be devised to understand and overcome drug resistance through the clinical assessment of rational therapeutic drug combinations and the use of biomarkers. Attempts to overcome resistance involves the use of combination drug therapy, p-glycoprotein modulators, epigenetic drugs, gene knockout using antisense oligonucleotides or ribozymes, interference and metronomic chemotherapy. Keywords: Cancer, Resistance, Chemotherapy. [Full Text Article] [Download Certificate] |
