Abstract

EVALUATION OF ANTHELMINTIC POTENTIAL OF ETHANOLIC EXTRACT OF LANTANA CAMARA STEMS

Anju Kumawat*, Narendra Vyas, Sapna Malviya and Anil Kharia

Abstract

Parasitic worms (helminths) of the gastrointestinal (GI) tract are pathogens of major global importance. Over a billion people, mainly in developing countries, are estimated to be infected with soil-transmitted helminths, whilst helminth infection is also a serious problem in livestock production worldwide, causing significant economic losses and threatening food security. Control of helminths relies almost exclusively on a limited number of synthetic anthelmintic drugs. Ethanolic extract of the stems of Lantana camara Linn were screened for its anthelmintic activity against Pheretima posthuma. The parameters like the time of paralysis and the time of death were determined by using the extract at the concentrations of 250 and 500mg/ml. The results of the study shows that ethanolic extract of stems of Lantana camara Linn showed significant anthelmintic activity at a dose of 500 mg/ml when compared to standard drug albendazole at 20mg/ml concentration.

Keywords: Anthelmintic activity, lantana camara, Ethanolic extract.