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WJPR

World Journal of Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

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ICV : 90.8

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	All	Since 2020
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Abstract

STUDY ON EFFECT OF PERMEABILIZERS ON POTENTIATION OF DIFFERENT ANTIBIOTICS AGAINST DRUG RESISTANT PSEUDOMONAS AERUGINOSA ISOLATES

Belani S. M.*, Verma A.K., Wadher B.J.

Abstract

Multiple drug resistant Pseudomonas aeruginosa is highly prevalent nosocomial pathogen responsible for unsuccessful of treatment therapies during various life threatening infections. In the current research work, effect of different concentrations of permeabilizers i.e. Citric acid, EDTA and Tris was studied against 57 clinical isolates of multiple drug resistant Pseudomonas aeruginosa. Significant potentiation was observed with Citric acid and EDTA while Tris does not show any sign of potentiation with different antibiotics used in the current study.

Keywords: Permeabilizers, Antibiotics, Pseudomonas aeruginosa, Resistant.

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