Abstract

A RANDOMIZED CLINICAL STUDY TO EVALUATE THE EFFECT OF SAMEERA PANNAGA RASA IN SANDHIGATA VATA W.S.R. TO OSTEOARTHRITIS

*Masand Sameet, Kashyap Chander Pal and Thakur Jyotsna

Abstract

Background: Osteoarthritis is a chronic degenerative disorder and a leading cause of chronic disability. According to WHO, OA is the second commonest musculoskeletal problem in world population after back pain. In Ayurveda there is very close relation in the symptoms of Sandhigata vata and Osteoarthritis. Ayurveda with its holistic approach can help in improving this condition with unique drug therapy and formulations. A Kupipaka Rasayana which is a sublimate material formed in glass bottle under graded heat was selected for the study because of its high efficacy with low dosage. Aims and Objectives: To evaluate the effect of an Ayurveda formulation named as Sammer Pannaga Rasa in restricting and minimizing the symptoms of Osteoarthritis in affected patients of age group ranges from 40 to 70 years. Materials and Methods: Total 15 patients were randomly selected for the clinical trial and administered with Sameer Pannaga Rasa 60 mg twice a day with Piper betel (Nagavallidala) or warm water. The efficacy of drug is evaluated on subjective parameters like visual analogue scale for pain, tenderness, edema etc. Results: Therapy shows maximum effect on edema with relief percentage of 66.66% followed by morning stiffness 57.14%, restriction of flexion 56.25% and Visual Analogue Scale of pain improvement of 51.28% with statistically significant p value of < 0.001. Conclusion: The therapeutic intervention improves the quality of life with reduction in intensity of pain and stiffness of joints.

Keywords: Osteoarthritis, Osteophytes, Kupipakwa, Visual analogue scale, Edema.