Abstract

PHARMACOGNOSTICAL AND PHARMACEUTICAL EVALUATION OF ASHWAGANDHADYA GHRITA - A COMPOUND AYURVEDIC FORMULATION

Kumari Archana*, Dr. D. B. Vaghela, Harisha C. R. and Shukla V. J.

Abstract

Karnanada is termed as tinnitus in modern medical literature: ringing in the ear causing great distress and emotional handicap. Tinnitus can lead to something more than a nuisance to the patient. Tinnitus is one of the most common and most prevalent ailments which we come across in our daily medical practice. Most studies agree that about one out of every 10 adults has tinnitus. It tends to be more common in those people who are working in noisy atmosphere. Vata –Rakta dominant Tridosha are the pathological factors in the disease of Karna -Nada. The treatment regimen is Ghritapana, Rasayana, Avyayama, Ashirasnana, Brahmacharya, Akatthana. The present study was carried out to standardize the finished product Medhya rasayana to confirm its identity, purity and quality. The presence of simple and compound grain with hilum, stained starch grain, pitted parenchyma with fibre, pitted vessels, cork, cortex, phloem, centrally wide vessels, xylem vessels, fibers, xylem parechyma & medullaryrays, xylem vessels, fibre, parenchma etc were the characteristic features of observed in microscopy of drug. Physico chemical analysis shows referactive index at 400 C is 1.47, specific gravity at room temp.at 32o C is 0.9144, acid value is 1.47, iodine value is 16.7, saponification value is 243.69. High Performance Thin Layer Chromatography (HPTLC) at 254 nm and 366 nm resulted into 7& 3 spots respectively.

Keywords: Ashwagandhadya ghrita, Karnanada, Pharmacognosy, Pharmaceutics, HPTLC.