Abstract

DETECTION OF ANTI-UROLITHIASIS ACTIVITY IN MALLIKAI CHOORNAM USING STRUVITE CRYSTAL GROWTH INHIBITION ASSAY

G. Rathiga*, T. Lakshmi kantham, K. Manikavasakam, V. Banumathi

Abstract

Urolithiasis is one among the three prevalent disorders in the urinary system. 10 -15% of urinary calculi are formed due to the presence of urease producing bacteria more prevalent in women. The present study was aimed to grow struvite crystals in vitro using single diffusion gel growth technique and to understand the effect of Mallikai Choornam on its growth. Test drug was prepared at two different concentrations of 0.5 and 1% dispersed in 1.0M magnesium acetate solution were gently poured on the set gel in the test tubes to enumerate the growth inhibition of struvite crystals. In the result of the study, it was concluded that the test drug Mallikai Choornam has shown inhibitory activity on struvite crystal growth.

Keywords: Urolithiasis, struvite, crystal growth, Mallikai choornam.