Abstract

A STUDY ON DRUG RELATED PROBLEMS IN CHRONIC KIDNEY DISEASE PATIENTS OF A TERTIARY CARE TEACHING HOSPITAL IN SOUTH INDIA

N.Vanitha Rani, Rini Thomas, Rohini E, P. Soundararajan G. Kannan,
P. Thennarasu

Abstract

Background: Chronic Kidney Disease (CKD) is a progressive condition with an increase in drug usage, resulting in increased prevalence of actual and potential drug related problems (DRPs) in these patients, posing significant challenge to health care providers. Objective: The aim of the study was to identify drug related problems in patients with chronic kidney disease (stages I to V), to resolve them by providing interventions to the health care providers and to educate the patients regarding the drug therapy. Methodology: A study was conducted in 226 patients (159 (70.4 %) males and 67 (30%) females), aged 18 years or older, diagnosed with all stages of Chronic Kidney Disease and hospitalized, including patients on maintenance hemodialysis and post renal transplantation. Patients data were collected by direct history interview and from the patient medical records, the prescriptions were analyzed and the DRPs were identified and classified and pharmacist intervention was done as per the simplified Iaser methodology. Descriptive analysis was done for age, drugs and DRPs and Kendall’s taub non-parametric test was used to assess the correlation between drugs prescribed and DRPs. All statistical tests were two tailed and P

Keywords: Drug related problems, hemodialysis, adherence, chronic kidney disease.