Abstract

PHARMACOGNOSTICAL AND PHARMACEUTICAL EVALUATION OF MANDURA VAJRA VATAKA - A COMPOUND AYURVEDIC FORMULATION

Sunita S. Vasaiya*, Devang Patel, Monika N. Solanki, Prof. Anup Thakar, Harisha C. R. and Shukla V. J.

Abstract

Anaemia is considered as a blood disorder characterized by low Haemoglobin level. Iron deficiency is the commonest nutritional deficiency in the world and its prevalence is highest in Indian population. According to the World Health Organization (WHO), there are two billion people with anaemia in the world and half of the anaemia is due to iron deficiency.[1] Mandura Vajra Vataka is compound of Ayurvedic formulation mentioned in Chakradatta, Pandu Chikitsa. Mandura Vajra Vataka contains Pippali, Amalaki, Bibhitaki, Vidanga etc. and Mandura Bhasma. The present study was carried out to standardize the finished product Mandura Vajra Vataka to confirm its identity, purity and quality. The presence of Black debris of Maricha, black deposition of ferric oxide, border pitted vessel of Pippali, Crystal deposition of cow’s urine, fragment of Devdaru etc. were the characteristic features of observed in microscopy of drug. Physico-chemical analysis shows loss on drying is 8.34% w/w, water soluble extract is 25.10% w/w, methanol soluble extract is 9.48% w/w, ash value is 60.88% w/w and PH is 6.5. High Performance Thin Layer Chromatography (HPTLC) at 254 nm and 366 nm resulted into 11 & 6 spots respectively.

Keywords: Mandura Vajra Vataka, Pharmacognosy, Pharmaceutics, HPTLC.