Abstract

FAST DISSOLVING TABLETS: A NOVEL APPROACH TO DRUG DELIVERY

Abstract

Fast dissolving tablets (FDTs) have received ever-increasing demand during the last decade, and the field has become a rapidly growing area in the pharmaceutical industry. Upon introduction into the mouth, these tablets dissolve or disintegrate in the mouth in the absence of additional water for easy administration of active pharmaceutical ingredients. The popularity and usefulness of the formulation resulted in development of several FDT technologies. Fast- or mouth dissolving tablets have been formulated for pediatric, geriatric, and bedridden patients and for active patients who are busy and traveling and may not have access to water. This article reviews the Need, advantages, challenges, limitations, mechanism of superdisintegrants, various formulation technologies (conventional and patented), marketed product of Fast dissolving tablets.

Keywords: Fast dissolving tablets (FDTs), Direct compression.