Abstract

PHARMACOGNOSTICAL AND PHARMACEUTICAL EVALUATION OF PHALAGHRITA - A COMPOUND AYURVEDIC FORMULATION

Anupam Gautam*, Dr. S. B. Donga, Harisha C. R. and Shukla V. J.

Abstract

Infertility is a burning problem of present era. In our classics mentioned a lots of preparations which is used in Infertility. Ayurvedic literature speaks about the importance of the drug “Nothing in the world exists, which does not have therapeutic utility”. W.H.O. has given a more comprehensive definition as “Drug is any substance or product that is used or intended to be used to modify or explore physiological systems or pathological status for the benefit of the recipient”. The importance of drug is very well known in all Ayurvedic classics and it has been highlighted by Acharya Charaka in Chikitsa Chatushpada. Chatushpada is required for the successful treatment of the disease. PHALAGHRITA is also a popular preparation which is used in different fields of infertility. Many Ayurvedic classics mentioned effectiveness of Phalaghrita especially for the treatment of Vandhyatva and other gynecological disorders. Aim: the present study was aimed at setting up a effectiveness of Phalaghrita in infertility caused by thin Endometrium which was prepared subjecting it to detailed pharmacognostical, physicochemical and phytochemical evaluation. Materials and Methods: Raw drugs of Phalaghrita were identified and authenticated by the Pharmacognosy Laboratory, I.P.G.T. & R.A., Gujarat Ayurved University, Jamnagar. Phalaghrita is prepared in pharmacy of I.P.G.T. & R.A., Gujarat Ayurved University, Jamnagar. Results: result of pharmacognostical study shows that the presence of Acicular crystals of Manjista, Prismatic crystals and Pitted vessels of Yastimadhu, Simple starch grains of Ashwagandha, Scleroids of Amalaki, Borderpitted vessels of Daruharidra, Borderpitted vessels of Daruharidra, Olioresine of Haridra, Pitted vessels of Kushta, Fibres with oil globules of Yavani, Cork in surface view of Shatavari, Prismatic crystals of Yashtimadhu. pharmaceutical analysis showed that loss on drying 0.3 % w/w, Specific gravity 0.9114, Refractive index 1.461, Acid value 2.83.analytical study showed 12 spots at 254 nm and 03 spots at 366 nm. conclusion: the findings of the study will be useful in the identification and standardization of the Phalaghrita.

Keywords: Phalaghrita, Thin Endometrium, HPTLC, Pharmacognosy, Pharmaceutics, Infertility.