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Abstract

ACUTE DIURETIC ACTIVITY OF A NEW FLAVONE GLYCOSIDE FROM THE STEMS OF TEPHROSIA PURPUREA LINN IN NORMAL RATS

R. N. Yadava and Prakrati Yadav

Abstract

Abstract: The aim of the present study is to isolate and structurallyelucidate a new flavones glycoside 5,7,3,4-tetrahydroxy-8-methoxyflavone-5-O-α-L-rhamnopyranosyl(16)O-β-Dglucopyranosyl(13)O-β-D-xylopyranoside together with twoknown compounds Apigenin and Kaempferol from the methanolicextract of the stems of Tephrosia purpurea Linn. and also evaluate thediuretic potential and effect on urinary electrolytes in normal rats. Thestructure was elucidated on the basis of various chemicaldegradations, color reactions and spectroscopic analysis.

Keywords: Tephrosia purpurea Linn., Leguminosae, flavone glycoside, Diuretic activity, Furosemide.


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