Abstract

ANTIMICROBIAL ACTIVITY AND MINIMUM INHIBITORY CONCENTRATION OF EHRETIA LAEVIS LEAVES EXTRACTS AGAINST DIFFERENT MICROORGANISMS

Kshama Murarkar* Ph.D, Diksha Bande and Anita Chandak Ph.D

Abstract

Ehretia laevis is a medicinal plants belonging to the Boraginaceous or Borage family. The present study aimed to evaluating the in vitro antimicrobial activity of acetone and isopropanol extracts of Ehretia laevis plants dried leaves against Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa. The extract was effective against Escherichia coli and Staphylococcus aureus. The minimum inhibitory concentration (MIC) of the all the extracts were found out by broth dilution method by taking extracts volume 1 ml and 5 ml respectively. The minimum inhibitory concentration of isopropanol extract was 1 ml and 2.5 ml, and for acetone extract was 2.5 ml and 1.25 ml respectively for S. aureus and E. coli.

Keywords: Ehretia laevis, Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa, minimum inhibitory concentration.