Abstract

PHYTOCHEMICAL INVESTIGATION AND IN VITRO ANALYSIS OF ANTIOXIDANT ACTIVITY OF OXALIS CORNICULATA

Anusha Govindula*, Nabeela Midhath, Syedahafsa Aqueel, M. Sowmya, K. Sandhya

Abstract

The aim of present study is to investigate the Phytochemical investigation of the Ethanolic extract of leaves of the plant Oxalis Corniculata belonging to the family- Oxalidaceae. The present study provides physicochemical and phytochemical details of the leaves of Oxalis Corniculata which are useful in laying down standardization and pharmacopeia parameters. The present study aims to open new avenues for the improvement of medicinal uses of Oxalic Corniculata leaves are selected for anti‐oxidant activity. The ethanolic extract of leaves of Oxalis Corniculata - Oxalidaceae were assessed for its antioxidant activity by Hydrogen peroxide scavenging activity, Total flavonoid content and Total Antioxidant Capacity by Phosphomolybdate method. In the H2O2 Radical Scavenging Activity, the % Scavenging Activity ethanolic extract of Oxalis Corniculata had shown better results with Standard α-tocopherol. Total Flavonoid Content was determined as Quercetin Equivalent dose. 1mg of the ethanolic extract of leaves of Oxalis Corniculata is Equivalent to 380 μg/ml of Quercetin Total Antioxidant capacity (%) was assayed by Phosphomolybdate method. The results were compared with standard and the extract had shown 74% while the standard had shown 59.64%.

Keywords: Antioxidant, Reactive Oxygen Species (ROS), Free Radical Scavenging Capacity, Total Flavonoids.