Abstract

COMPUATATIONAL ANALYSIS AND STRUCTURAL CHARECTERIZATION OF ODORANT-BINDING PROTEIN, BOMBYX MORI

Vijina Chakkyarath*, S. Manthira Moorthy and V. Sivaprasad

Abstract

The period of Computational biology play a broad position in the characterization of proteins, molecular modeling and drug studies. In this study, proteomic tools and computational methods are used to characterize the 7-odorant binding proteins of Bombyx mori, which is retrieved from the Swiss-prot Database. Odorant binding proteins are considered to be responsible for the transport of pheromones and also cell signaling. It is present in the olfactory receptors of B. mori. Through sequence analysis, we found the similar sets of Protein sequences (hits) and through structural analysis, we could characterize the protein by primary as well as the secondary structure analysis. Subcellular location prediction helped to find location assignment of 7 odorant binding proteins. Finally through homology modeling method we modeled 7 odorant binding protein for further future Perspectives. Modeled quality has checked using Ramachandran plot analysis.

Keywords: 7-odorant binding proteins and Bombyx mori.