Abstract

EVALUATION OF CYTOTOXIC POTENTIAL OF TERMINALIA BELLERICA ROXB SILVER NANOPARTICLES AGAINST PANCREATIC CANCER ASPC-1 CELL LINE

Sivaranjani D.* and Bharathi V.

Abstract

Silver is a second most valuable metal in the world which might be used for ornamental as well for medical treatment purposes. After the arrival of nanotechnology in science field,the treatment of diseases become more advanced than compared to previous era, Nanoparticles green synthesis from plants also possess excellency in the pharmacological area. However, the silver nanoparticles from Terminalia bellerica roxb in the treatment of cancer is taken for the present study, the UV-Vis, FT-IR, SEM analysis revealed the potency of silver nanoparticles of Terminalia bellerica Roxb in pancreatic cancer cell line AsPC-1. The MTT study shows the maximum anticancer activity against AsPC-1 of Terminalia bellerica roxb. In the present study, We critically assess the role of silver nanoparticles in biomedical application.

Keywords: FT-IR, MTT assay, SEM, Terminalia bellerica roxb, UV- Vis.