Abstract

IDENTIFICATION OF SOME BIOACTIVE CONSTITUENTS OF GLYCOSMIS PENTAPHYLLA RETZ. DC. USING GC-MS

M. Sivakumar, D.Chamundeeswari, Nalini Ganesan and Hannah. R .Vasanthi 

Abstract

Glycosmis pentaphylla commonly known as “Anam” in Tamil is a medicinally important plant belonging to the family Rutaceae. The leaves are used in traditional medicine for the treatment of fever, hepatopathy, helminthiasis, wounds, eczema, erysipelas and other skin diseases. The fruits are useful in vitiated conditions of vata, pitta and kapha. The roots are effective in treating facial inflammations, rheumatism, jaundice and anaemia. A study was conducted with the objective of identifying some new chemical constituents present in the ethanolic extract of the roots of Glycosmis pentaphylla by subjecting it to GC-MS analysis. Twenty five chemical constituents have been identified, of which six were for the first time identified major constituents namely 7H-Furo (3,2-G) (1)Benzopyran-7-one,2,3 – dihydro – 2 - (1-Hydroxy-1methylethyl) - (s) - (10.96%), Stimast-5-en3-yl-9-octadecenoate (9.06%), Gama.-Sitosterol (8.84%), 5-hydroxypipecolic acid(6.23%), (-)-Guaiol (5.58%), 1H-Indole-3-Ethanamine, 5-Methoxy-N, 1- Dimethyl (5.81%).

Keywords: Glycosmis pentaphylla, ethanol root extract, phytochemicals, GC-MS analysis.