WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
Best Paper Award :
Dr. Dhrubo Jyoti Sen
Download Article: Click Here

Search

Track Your Article

Abstract

ANTIHYPERTENSIVE AND LIPID LOWERING EFFECT OF TERMINALIA ARJUNA (AQUEOUS EXTRACT) IN SPONTANEOUSLY HYPERTENSIVE RATS (SHR): AN EXPERIMENTAL STUDY

Srivastava Pooja*, Bajpai Manish, Kumar Pradeep, Tiwari Sunita and Singh Kalpana

Abstract

Hypertension is one of the leading causes of death in developed as well as in developing countries. Essential hypertension is accounting for 90 percent of all cases of hypertension. Alternative methods including supplementation with various herbs offer an effective way to decrease the rising number of people with high blood pressure. Terminalia arjuna (TA) is reported to be used in Indian medicinal system (Ayurveda) since thousands years. Exact mechanism responsible for reduction in blood pressure by Terminalia arjuna yet to be proved. In, present study we examined the effect of TA on various lipids in hypertensive rats. The study was conducted on 30 spontaneously hypertensive rats (SHR) divided in to five groups. Group I treated as control and Group II a, b, c treated with aqueous extract of Terminalia arjuna (AETA) in various doses. Group III was treated with known hypotensive drug enalapril. After 4 weeks of experimental protocol, blood pressure, heart rate, total cholesterol, triglycerides, high density lipoprotein (HDL) cholesterol were measured. The present study shows that the Terminalia arjuna has potential to lower serum cholesterol, serum triglyceride, very low density lipoprotein (VLDL) and low density lipoprotein (LDL) and significantly decreases the blood pressure and heart rate in SHR rats.

Keywords: Terminalia arjuna, SHR Rats, Hypertension, Lipid Profile.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More