Abstract

A PROMISING APPLICATION OF BACTERIOCIN AGAINST FUNGAL INFECTIONS

Dr. Sabiha Imran*

Abstract

Mycoses are diseases caused by fungi. Mycoses have become a growing problem in modern medical care with the increase in the population of patients with immunodeficiency or undergoing immunosuppressive therapy. The diagnosis of these diseases can be problematic, drug resistance is of great concern and fewer drugs are available compared to bacterial or viral diseases. Fungal infections lead to various diseases that can be Local, superficial, allergic or systemic. For the treatment of fungal infections bacteriocins have very promising candidate as antifungal agent. Bacteriocins are ribosomally synthesized antimicrobial peptides, have traditionally been used as food preservatives, either added or produced by starter cultures during fermentation. In-depth studies of a select few bacteriocins opened exiting new research fields and broadened the application of these antimicrobial peptides. The application of the produced antimicrobial compounds as a natural barrier against fungal pathogens have been proven to be efficient. The present review focus on the bacteriocins unique properties which could be explored and utilized as an antifungal agent

Keywords: Antifungal agents, Bacteriocin, antimicrobial, fungal infections.