Abstract

PHYTOCHEMICAL AND ANTIMICROBIAL ANALYSIS OF SENNA ALATA LEAVES EXTRACT

J. Jayachitra*, K. Pavithra, R. Suja pandian V. Bharathi, S. Shanthi

Abstract

Objectives: Ethanolic extrat of Senna alata leaves leaves was investigated for antimicrobial activities. Methods: The well diffusion method was followed for antibacterial assay. Antimicrobial activity of the leaves extract (200μg,400μg, 600μg and 800 μg) using well diffusion method. In this disc was prepared by using whatmann No.1 filter paper. Then, the filter paper disc of 5mm diameter were sterilized and soaked in the different concentration of plant extract. Results: The increase in prevalence of multiple drug resistance has slowed down the development of new synthetic antimicrobial drugs and has necessitated the search for new antimicrobials from alternative Sources. In the present investigation, preliminary phytochemical analysis was carried out in the extracts of Senna alata. Conclusion: In the present investigation, preliminary phytochemical analysis was carried out in the extracts of Senna alata. The extracts showed the presence of alkaloids, reducing sugar, coumarin, tannin and phenolic compounds.

Keywords: Streptococcus pneumonia, Proteus.sp and Enterobacter sp.