Abstract

METABOLIC SYNDROME AND ITS EFFECTS – A REVIEW

S. Arshad, D. Sudheer Kumar and P. Kishore*

Abstract

Metabolic Syndrome is defined as a group of various risk factors which includes physiological, biochemical, clinical and metabolic factors that increases the risk of ASCVD, Type II DM and mortality. Clinically there are various diagnostic criteria for defining metabolic syndrome. Most of the features are common for diagnosing in each definition but they vary slightly in few parameters. The prevalence of Metabolic syndrome across the world is based on the area, age, sex, race, ethnicity of the studied population by using different definitional criteria it ranges from less than 10% to nearly 80%. India occupies one quarter (25%) of population with metabolic syndrome when they have used WHO or ATP III criteria for defining metabolic syndrome. Abdominal Obesity and Insulin resistance are the main factors that are linked up with many other parameters, which can cause metabolic syndrome. The effect of metabolic syndrome on cardiovascular and renal system is observed and there is an increased risk of cardiovascular and renal complications with metabolic syndrome components if it is not prevented and not controlled. Clinical pharmacist plays a vital role in health care systems by educating the patients regarding metabolic syndrome progression and importance of medication adherence and suitable lifestyle modifications (such as dietary intake and regular exercise) for better longevity and good quality of life.

Keywords: Metabolic syndrome, Risk factors, Insulin Resistance, Abdominal Obesity.