Abstract

EVALUATION OF ANTIPSYCHOTIC AND ANXIOLYTIC ACTIVITY OF ALOE VERA (ALOE BARBADENSIS MILLER) IN RATS

Kiran Kumar Donthula* and Shravan Kumar Dholi

Abstract

In recent years, there has been much focus on the apparent heterogeneity of schizophrenic symptoms. By contrast, this article proposes a unifying account emphasizing basic abnormalities of consciousness that underlie and also antecede a disparate assortment of signs and symptoms. Schizophrenia, is fundamentally a self-disorder or ipseity disturbance is characterized by complementary distortions of the act of awareness, hyper reflexivity and diminished self-affection. Anxiety impacts people in ways that they are unaware. In the presence of anxiety, attention is highly directed towards threatening information. Recently, anxiety was found to impact task switching performance when threatening stimuli were present. In the current study, we examined the Anxiolytic and antipsychotic activity of Aloe vera (Aloe barbadensis miller) in rats. This study reveals that the Aloe vera has showed decreased effects of turning behaviour, weaving behaviour, head bobbing and falling behaviour. It also showed decreased effect of loco motor activity and increase in catalepsy scoring. Thus it shows anti psychotic and anti anxiety effects.

Keywords: Schizophrenia, Anxiety, Aloe vera.