FORMULATION DEVELOPMENT AND EVALUATION OF UNIT MOULDED SEMISOLID JELLY FOR ORAL ADMINISTRATION AS A CALCIUM SUPPLEMENT
Tanu Godhwani1, Mahavir Chhajed2*, Atika Chhajed3, Deepshikha Tiwari1
Abstract
The present study was conducted with an aim to formulate and
evaluate the unit molded jelly containing calcium supplement and
optimization of this dosage form which will dissolve slowly when
kept in contact with mouth without any irritation or inflammation and
bitter after taste. The oral route of administration is the preferred route
of drug delivery. Now-a-days, jelly candies have become very
common in children as they enjoy chewing the jelly. The formulation
of jelly is advantageous for drug delivery in paediatric patients and
may also be used in the cases where tablet or capsule swallowing is
difficult. The jellies were evaluated for their physiochemical
parameters like Color, taste loss on drying, pH, spreadability, test for
presence of heavy metals and stability studies. All the ten formulation
(F1 to F10) under study was found to be stable and showed
comparable appearance, pH, spreadability and viscosity. The article describes about the
formulation aspect of jelly, excipients and flavors employed and the evaluation parameters
along with the drug used in the formulation. The optimized formulation F4 was found to be
stable for the period of 3 months as per ICH guidelines.
Keywords: Jelly formulation, calcium supplements, unit molded dosage, physiochemical parameters.
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