Abstract

AN OBSERVATIONAL STUDY OF PATTERN AND ASSOCIATION OF THYROID HORMONES IN VARIOUS CONDITIONS

B. Anoosha, P. Kishore, B. Sridhar, D. Sudheer Kumar and R. Deepthi*

Abstract

Background: Thyroid dysfunctions are the most common endocrine disorders seen in the population. Their signs and symptoms may be subtle, non-specific and they can be incorrectly attributed to other illnesses. This study was aimed to assess the thyroid hormones pattern in various conditions and their interrelationship. Method: It is a hospital based observational study conducted in 464 patients with thyroid dysfunction at an Endocrine Clinic, Hanamkonda for a period of 6 months. Results: Among 464 patients enrolled with thyroid dysfunction, female population were predominant (89.87%). Most prevalent thyroid disorders associated was hypothyroidism (78.01%). The mean age of the study population was 36.55 years. Of all the co morbidities associated with thyroid dysfunction, diabetes (40.51%) was found to be in higher rate. Among 180 pregnant women, hypothyroidism was the most observed thyroid dysfunction. Prevalence of both hypothyroidism (46.25%) and hyperthyroidism (56.52%) was observed predominantly in second trimester. Conclusion: Early diagnosis and proper management of thyroid disorders may prevent patient’s risk from acquiring other co morbid conditions. Annual screening is recommended for all age groups. For pregnant women, thyroid evaluation in each trimester is beneficial.

Keywords: Hypothyroidism, Diabetes, PCOS, HTN.