Abstract

ANTIMICROBIAL RESISTANCE AND PROBIOTICS

Mahi Tyagi*, Sonali Gangwar and Maya Datt Joshi

Abstract

Antibiotics were discovered either to kill microbes or to inhibit the growth of bacteria causes disease and diminish human health. Several factors like overuse of antibiotics, incomplete course of antibiotics by patients, over- prescription, poor hygiene control in health care units gave birth to resistant microbes against antibiotics. Today antimicrobial resistance is becoming a major concern globally. These resistant microbes are becoming challenge for scientist working on drugs, pharmaceutical industries and healthcare units. Their multi drug resistance ability making several of resistant microbes more complex in dealing and listing them in deadly pathogen list. These microbes are depleting the natural gut environment by promoting gene of resistance to the gut microbiota leads to several health problems. Such new resistance mechanisms are spreading globally threatening our ability to treat common infectious diseases, resulting in prolonged illness, disability and death. Probiotics are live micro-organisms that are generally regarded as safe, can reduce antibiotic consumption and improve human health largely because of their anti-carcinogenic, anti-allergic and anti –inflammatory properties. Introduction of Probiotics can help to resolve this global problem to some extent.

Keywords: Antibiotic, Gut Microbiota, Antimicrobial Resistance, Probiotics.