Abstract

EVALUATION OF ANTI-OXIDANT PROPERTY OF SIDDHA HERBAL FORMULATION "THOOTHUVELAI KARPAM''

Rahini Nivedhidha C.*, Ranjitham K., Sivakkumar S., Visweswaran S., Maariappan A. and Banumathi V.

Abstract

Siddha system of Medicine is one of the ancient systems of medicine in India. Siddha medicine serves both therapeutic and prophylactic concepts and hence Holistic in nature. Kaya Karpam, a special branch of this medical system is a science of rejuvenation, longevity, and spiritual wellbeing. Concept of Kaya Karpam was briefly explained by saint Thirumoolar in his text Thirumanthiram. The word Kaya and Karpam denotes the meaning of Prevention of body from diseases. Nowadays, this can be correlated with the Anti-Oxidant concept. It deals with the Prevention of Narai (Whitening of hairs), Thirai (Shrinking of Skin), Moopu (Aging), Saakadu (Death). Majority of the diseases/disorders are mainly linked to oxidative stress due to free radicals. A plant-based drug protects against chronic oxidative stress-related diseases. Kaya Kalpa drugs have proven scientific evidences to prevent and manage the Non communicable diseases like Diabetes mellitus, Obesity and also Chronic deliberating diseases like cancer etc. This study is aimed to screen the antioxidant effect of Thoothuvelai Karpam by using DPPH free radical scavenging assay, Nitric Oxide radical scavenging, ABTS radicals, Hydrogen Peroxide Radical Scavenging Assay. The results of this study shows that the percentages of inhibition in DPPH, Nitric Oxide and ABTS, Hydrogen Peroxide radical scavenging studies are 50.73% (standard ascorbic acid 86.07%), 69.38% (standard Gallic acid 91.38%) and 67.1% (standard Gallic acid 94.48%), 70.74% (standard BHA 89.98%) respectively and thus, our findings provide evidence that Thoothuvelai Karpam could be a potential source of natural antioxidant and it may be used as rejuvenating medicine for vast therapeutic effects, gives a powerful body, mind and soul with long-lasting life.

Keywords: Thoothuvelai karpam, Kayakalpam, Siddha medicine, Antioxidant.