Abstract

PHARMACOGNOSTICAL AND PHARMACEUTICAL EVALUATION OF KALYANAKA GHRITAM IN THE MANAGEMENT OF UNMADA W.S.R. TO SCHIZOPHRENIA

Dr. Binal J. R.*, Dr. Alankruta Dave and Harisha C. R.

Abstract

The most dreadful and vulnerable disorder among mental illness is schizophrenia. It affects about 1.5% of the adult population, usually begins before the age 25, persists throughout life, and affects persons of all classes. Although schizophrenia is discussed as if like a single disease, it probably comprises a group of disorders with heterogeneous etiologies, variations in clinical presentations and response to treatment and course of the illness. It is mainly characterized by specific psychological symptoms that interfere with the thinking, emotions, conation and motor behavior of the patient. And moreover, in chronic stage, certain symptoms, which are often called negative symptoms, make the patient„s condition to worsen. In Ayurvedic classics, Unmada is the term used to denote mental illnesses which are characterized by the perversion of mind, intellect, consciousness, knowledge, memory, desire, manners, behaviors, and conduct2 and is said to be manifested as a result of the occlusion in the Manovaha Srotas by various etiological factors. Kalyanaka ghrita is well proved n management of the Unmada and Anidra. For the first time Pharmacognostical & Analytical study of Kalyanaka ghrita has been carried out for the evaluation of its efficacy in the schizophrenia. Pharmacognostical results showed fibers through medullary rays, Pitted vessels, Par-Starch, Sceried, Trichome, Mesocarp. The Analytical study showed that loss of drying 0.82%, acid value 0.354, Iodine value 57.23, saponification value- 177.62. The details will be describe in full paper.

Keywords: Schizophrenia, Kalyanaka ghrita, Unmada, Psychosis.