Abstract

ELUCIDATION OF IN VITRO ANTI- INFLAMMATORY ACTIVITY OF CINNAMOMUM ZEYLANICUM BY HRBC MEMBRANE STABILIZATION AND PROTEIN DENATURATION

Jain Suransh, Dr. Vikram Kumar*, Prof. (Dr.) A.N.Pathak

Abstract

The bark extract of Cinnamomum zelanicum were assessed for In-vitro Anti-Inflammatory activity by HRBC membrane stabilization method and Inhibition of protein denaturation method. The presence of flavanoids has been reported earlier in C.zeylanicum. Since the flavanoids have remarkable anti-inflammatory activity, so the present work aims at evaluating the anti-inflammatory activity of C.zeylanicum. Different concentrations of extract were compared against standard Diclofenac sodium. Maximum stabilization in our study is 68.41 % at 1000 μg/ml and maximum inhibition is 78.30% at 1000 μg/ml. Therefore, our studies support the use of C.zeylanicum in treating inflammation.

Keywords: Cinnamomum zelanicum, HRBC, Diclofenac sodium, Anti-Inflammatory.