WJPR
World Journal of Pharmaceutical Research
( An ISO 9001:2015 Certified International Journal )
An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
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WJPR Citation
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| All | Since 2011 | |
| Citation | 2903 | 2393 |
| h-index | 27 | 24 |
| i10-index | 68 | 60 |
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Best Paper Award : Dr. Dhrubo Jyoti Sen
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Abstract
CHEMICAL COMPOSITION AND ANTICANCER ACTIVITY OF DALDINIA CONCENTRICA (XYLARIACEAE)
Boua Benson Boua*, Minhinle Arsène Christel Oulaguehi, Guy Roger Mida Kabran, Janat Akhanovna Mamyrbekova-Bekro, Marc Lecouvey and Yves-Alain Bekro Abstract The mycochemical study of hexanic (EH), ethyl acetate (EE), and ethanolic extracts (EET) of Daldinia concentrica by thin layer chromatography revealed the presence of terpenes, sterols and coumarins. The presence of flavonoids and quinones has been mentioned only in the ethyl acetate and ethanolic extracts. In vitro bioassays performed on the CA 431 cell line, showed the anticancer activity of the extracts with a greater efficiency for the ethanolic extract (IC50 = 0.03 mg / mL), which seems to depend on the coexiting conjugated secondary metabolites detected. Keywords: Daldinia concentrica, chemical composition, anticancer activity. [Full Text Article] |
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