Abstract

PHYTOCHEMICAL SCREENING AND ANTIMICROBIAL POTENTIAL OF MELIA AZEDARACH BARK EXTRACTS FOR DEVELOPING HEALTH CARE TEXTILE MATERIALS

Kalaiselvi E.*, Yasotha P. and Dr. K. M. Pachiyappan

Abstract

The textiles are not only the carrier but also an excellent media for the development of microorganisms, due to side effects and water pollution caused by synthetic antimicrobial agents there is a great need of antimicrobial textiles in particular for healthcare products from natural sources. The Melia azedarach was prepared using solvents namely methanol, ethanol, ethyl acetate, aqueous, acetone and chloroform.The present study was designed to check the preliminary phytochemical screening and to identify the antibacterial activity of Melia azedarach bark extracts. The prepared solvent extracts showed the presence of various phyotochemicals specifically terpenoids, alkaloids, glycosides, tannins, phenols. The M.azedarach bark extracts are tested against two test bacteria’s Staphylococcus aureus and Escherichia coli using disc diffusion method. The concentration study was carried out to selected best concentration withhigher zone of inhibition. The optimized parameters were used for fabric finishing and tested against two bacteria’s Staphylococcus aureus and Escherichia coli and two fungus Aspergillusniger and Malassezia furfur. The cotton linen blended fabric treated with Melia azedarach bark extract shows32mm and 29mm zone of inhibition against s.aureus and E.coli and 57mm and 55mm zone of inhibition against A.niger and M.furfur respectively.

Keywords: Melia azedarach, solvents, phytochemicals, secondary metabolites, antimicrobial, cotton linen blended fabric.