Abstract

COMPARISON OF RESPONSE ASSESSMENT TO NEO-ADJUVANT CHEMOTHERAPY IN LARGE OPERABLE AND LOCALLY ADVANCED BREAST CANCER BY CLINICAL METHODS, MAMMOGRAPHY AND ULTRASONOGRAPHY

Dr. Bidyut Biswas, *Dr. Swapan Kumar Mallick and Dr. Ghafran Nahid

Abstract

Breast Cancer is the most common female cancer in the world. It is leading cause of Cancer mortality among woman aged 20-59 years.The aim of screening of breast cancer is to identify preinvasive disease or invasive disease before dissemination.In our study twenty patients of histologically proved and locally advanced breast cancer were evaluated for response to Neo-Adjuvant chemotherapy were assessed by clinical methods. Mammography and USG after 2nd and 4th cycle of chemotherapy and results were compared. Again post operative histopathological examinations of the specimens were compared to the results of clinical methods, mammography and USG. It is seen that triple assessment is better than any single modality of response assessment. In our study, the response to neoadjuvant chemotherapy was assessed by mammographic response in 17 cases and by ultrasonography in 16 cases. Mammography response was seen 82% cases (15).

Keywords: Neo-adjuvant Chemotherapy, Clinical Method, Mammography, Ultrasonography.