Abstract

POTENTIAL TEST AND COMPARATIVE TEST OF AMOXYCILLIN ANTIBIOTICS USED IN THE TREATMENT OF CASES OF RESISTANCE IN TASIKMALAYA, INDONESIA

Dr. Danni Ramdhani*, Sri Agung F. K. and Rurynta F. S.

Abstract

Objective: ARI is an acute infection of any part of the respiratory tract including the paranasal sinuses, middle ear and pleural cavity caused by viruses, bacteria, rickettes. Amoxycillin is one of antibiotics to overcome the disease ARIs. Ineffective use of antibiotics may lead to resistance. The potential value of antibiotics determines the effectiveness of an antibiotic. This study aims to determine the potential value and comparative test of amoxycillin antibiotics as a quality evaluation. Methods: Test the antibiotic potency with diffusion method to use 3 doses with using antibiotic samples. Comparative test of antibiotic testing by comparing samples with standard against E. coli ATCC 25922 test bacteria. Results: The potential value obtained was 96.16%, and comparative test was 1 : 1,01. Conclusion: The results of testing the potential of amoxycillin in accordance with the requirements contained in Indonesia Pharmacopeia. The comparative test results show that antibiotic samples used had good bacterial killing ability.

Keywords: Amoxycillin, antibiotic resistence, potential test, comparative test, agar diffusion.