Abstract

A CASE REPORT ON ATT INDUCED DYSTONIA WITH HEPATITIS

G. Sarah Marlyn*, Neelam Injeti, Safura Tasneem and Ayesha Sami Uddin

Abstract

Anti-tuberculosis therapy is a goal standard therapy for active TB. The regimen involves Isoniazid, Rifampicin, Ethambutol, Pyrazinamide and Streptomycin. These drugs are given generally in multi-drug combination therapy depending on the requirement of the patient and the severity. These drugs have been associated with a variety of adverse effects ranging from mild to severe. Ototoxicity and Hepatotoxicity are common. Hepatitis and neuropathy leading to involuntary muscle movement (dystonia) has also been noted which is the drug induced condition in this patient.

Keywords: Anti tuberculosis therapy, Involuntary muscle contractions, Myopathy, Neuropathy, Hepatotoxicity.