Abstract

A REVIEW ON ALTERNATIVE ROUTES FOR INSULIN ADMINISTRATION

Ch. Amulya*, Dr. M. Eswar Gupta and Dr. I. Sudheer Babu

Abstract

Many routes were tried to administer insulin into the body. Intramuscular, intravenous and subcutaneous routes were first tried. Among them, subcutaneous and intravenous routes are commonly used routes of administering insulin. These routes need injectible methods to deliver insulin which causes lot of pain and discomfort to the patient. To make insulin delivery in an easier and simpler way and to increase comfort in patients, other routes of administration were also tried. These include oral, buccal, sublingual, rectal, transdermal, ocular, intrapulmonary, and intranasal routes. This article gives a bird’s eye view of research carried out till date to administer insulin in a convenient route other than injectible route.

Keywords: Insulin, Diabetes, Intra pulmonary route, Intra nasal route.